Which statement about decontamination sequencing is correct?

Which statement about decontamination sequencing is correct?

• A. Sterilizing then cleaning
• B. Disinfection then cleaning
• C. Cleaning then sterilizing
• D. Cleaning only

Answer: (C)

Cleaning first is essential because it removes dirt and organic matter that can shield microorganisms and block the sterilant from reaching all surfaces. Once the item is clean, sterilizing can effectively kill all microorganisms, including spores, giving true decontamination. If you sterilize before cleaning, soil can prevent penetration of the sterilant and leave microbes alive. While disinfection has its place for certain items or situations, it does not replace the need to clean prior to sterilization. Cleaning alone won’t achieve complete decontamination for instruments that require full sterility, so the proper sequence is to clean first and then sterilize.

Cleaning first is essential because it removes dirt and organic matter that can shield microorganisms and block the sterilant from reaching all surfaces. Once the item is clean, sterilizing can effectively kill all microorganisms, including spores, giving true decontamination. If you sterilize before cleaning, soil can prevent penetration of the sterilant and leave microbes alive. While disinfection has its place for certain items or situations, it does not replace the need to clean prior to sterilization. Cleaning alone won’t achieve complete decontamination for instruments that require full sterility, so the proper sequence is to clean first and then sterilize.